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The Nerves of the Squid

15/10/2015

 
The knowledge of the physico-chemical functioning of life made its breakthroughs in the mid-twentieth century helped of course by the X-rays but also by the improvement of electricity and electronics.

Alan Hodgkin and Andrew Huxley are biophysicists and more exactly electrophysiologists. The new technique of the voltage clamp allows them to measure the electric signal across the membrane of a nerve cell.

The sciatic nerve of the frog did not allow measurements in a sufficient accuracy. Working in association with the marine biology laboratory of Plymouth in England, they use in their experiments the largest known axon in the animal reign, measuring 1 mm in diameter, used by the squid to elicit a quick reaction to a threat.

The two researchers can then model the electrical behavior of the neuron. This fruitful advance will have a considerable impact on the knowledge and healing of several nerve diseases and will enable to raise a model of the transmission of nerve inputs to the muscular system. The existence of ion channels in cell membranes will be confirmed by others much later, completing the description of the nervous cell.

Hodgkin and Huxley shared the 1963 Nobel Prize in Physiology or Medicine with John Eccles. The Nobel medal awarded to Hodgkin will be sold with various documents including a copy of the scientific publication associated with the prize as lot 1 in an online timed auction ending on October 29. The minimum bid is $ 450K.

The auction house, Nate D. Sanders, is based in Los Angeles. It is gradually becoming a leader in the growing market for Nobel medals, with successful sales reminded below.

The Nobel Prize in Economic Sciences of Kuznets (1971) was sold for $ 390K on 26 February 2015. The Nobel Prize in Chemistry of Wieland (1927) was sold for $ 395K on 30 April 2015. The Nobel Prize in Physics of Lederman (1988) was sold for $ 765K on 28 May 2015. These prices include the premium.

​SOLD for $ 800K including premium
Medal and Decoration

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    by 'Pierre'

    Pierre Tavlitzki
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